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geninventorprofessi...Gastric secretion in the dog is stimulated by cholinergic drugs and is inhibited by muscarinic cholinergic antagonists. The nature and the mechanism of the cholinergic mediation of gastric acid and pepsinogen secretion are not clear. In an attempt to examine whether vagal cholinergic mechanisms are involved in the stimulation of gastric secretion, we used drugs that inhibit or stimulate the muscarinic cholinergic receptors, and monitored the acid and pepsinogen secretions in anesthetized dogs. Gastric acid secretion was increased significantly by i.v. injections of acetylcholine or a muscarinic cholinergic receptor agonist, and it was decreased by atropine, methoctramine or pirenzepine. Gastric pepsinogen secretion was increased significantly by a cholinergic drug and decreased by atropine, but was unaffected by methoctramine or pirenzepine. In a separate series of experiments, i.v. administration of a muscarinic cholinergic receptor antagonist did not modify basal gastric acid or pepsinogen secretion. In conclusion, the results obtained in this study indicate that a cholinergic stimulatory mechanism is involved in gastric acid and pepsinogen secretion in the dog and that muscarinic cholinergic receptors, located on the parietal cells, may be involved in the mechanism of the cholinergic action on acid and pepsinogen secretion.Q: How to read the XML document file with openXML? I'm trying to read the xml file that I created by an ASP.NET application. XMLDocument doc = new XMLDocument(); doc.Load(Server.MapPath("XmlFile.xml")); This XML file is stored in a folder on my Web Server. I wrote an application that reads the file using the above code. But when I try to write a code to read the file, I'm getting an exception. To Read: using (XmlReader reader = XmlReader.Create(Server.MapPath("XmlFile.xml"))){ while (reader.Read()) { if(reader.Name.Equals("Line")){ //do something }
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